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By Barbara Forney, VMD
Last reviewed: 9/20/2022
Commonly prescribed for: Rescue Protocols for Relapsed Canine Lymphoma; Cutaneous Lymphoma of Dogs; Relapsing Lymphosarcoma in Cats
Species: Dogs and Cats
Therapeutic Class: Chemotherapeutic Alkylating Agent.
Lomustine is a chemotherapeutic alkylating agent. It also commonly is referred to as CCNU. Alkylating agents disrupt DNA transcription and RNA replication. They are not cell-stage specific. Lomustine is metabolized in the liver and excreted in the kidneys. It is highly lipid-soluble and crosses the blood-brain barrier into the CNS. Lomustine is absorbed rapidly from the GI tract. In order to decrease nausea, lomustine should be given on an empty stomach. There is some topical absorption of lomustine.
We can let your veterinarian know that you are interested in our compounded Lomustine.
Dosage options starting at $1.87 per dose
Oral medication available in gelatin or veggie capsule options.
Flavored, medicated oral soft chew treats.
Oil based oral suspension with a wide variety of flavoring options.
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This content is intended for counseling purposes only. This content is informational/educational and is not intended to treat or diagnose any disease or patient. No claims are made as to the safety or efficacy of mentioned preparations. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. You are encouraged to speak with your prescriber as to the appropriate use of any medication. Wedgewood Pharmacy’s compounded veterinary preparations are not intended for use in food and food-producing animals. All product and company names are trademarks™ or registered® trademarks of their respective holders. Use of them does not imply any affiliation with or endorsement by them.