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By Barbara Forney, VMD
Last reviewed: 7/12/2022
Commonly prescribed for: Functional Urethral Obstruction; Malignant Hyperthermia; Canine Stress Syndrome; Exertional Rhabdomyolysis
Species: Dogs, Cats, and Horses
Therapeutic Class: Skeletal Muscle Relaxant
Dantrolene sodium (DS) is a non-centrally acting skeletal muscle relaxant. It interferes with normal excitation/contraction coupling. Although the mechanism of action is not understood completely, it is thought to interfere with the release of calcium from the sarcoplasmic reticulum by interfering with a specific receptor. DS does not interfere with cardiac and smooth-muscle contraction because the mechanism of calcium release in these types of muscle is under different control. DS is used in humans primarily for upper motor neuron disorders. It is metabolized by the liver and excreted in urine.
We can let your veterinarian know that you are interested in our compounded Dantrolene Sodium.
Oil based oral suspension with a wide variety of flavoring options.
Flavored oral paste, packaged in a dosing syringe.
Flavored oral dry dosage form, ideal for mixing in food.
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This content is intended for counseling purposes only. This content is informational/educational and is not intended to treat or diagnose any disease or patient. No claims are made as to the safety or efficacy of mentioned preparations. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. You are encouraged to speak with your prescriber as to the appropriate use of any medication. Wedgewood Pharmacy’s compounded veterinary preparations are not intended for use in food and food-producing animals. All product and company names are trademarks™ or registered® trademarks of their respective holders. Use of them does not imply any affiliation with or endorsement by them.