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By Barbara Forney, VMD
Last reviewed: 7/12/2022
Commonly prescribed for: Chemotherapy
Species: Dogs and Horses
Therapeutic Class: Platinum-containing Chemotherapy
Cisplatin is a platinum-containing chemotherapy drug. Although the mechanism of action is not understood completely, cisplatin behaves similarly to a bi-functional alkylating agent by producing cross links in DNA. Cisplatin is distributed widely into the liver, kidney and intestines and is distributed poorly into the central nervous system (CNS). Cisplatin is particularly nephrotoxic and approximately 50% of cisplatin is excreted by the kidneys in the first 24 to 48 hours. It is activated in the kidneys to produce a metabolite that is toxic to the proximal tubule cells.
We can let your veterinarian know that you are interested in our compounded Cisplatin.
Dosage options starting at $11.15 per dose
Sterile suspension intended for injection.
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This content is intended for counseling purposes only. This content is informational/educational and is not intended to treat or diagnose any disease or patient. No claims are made as to the safety or efficacy of mentioned preparations. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. You are encouraged to speak with your prescriber as to the appropriate use of any medication. Wedgewood Pharmacy’s compounded veterinary preparations are not intended for use in food and food-producing animals. All product and company names are trademarks™ or registered® trademarks of their respective holders. Use of them does not imply any affiliation with or endorsement by them.