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Progesterone is a steroid hormone normally produced by the corpus luteum and by the placenta of pregnant mares. Exogenous progesterone is used to prevent mares from coming into heat, to synchronize estrus cycles of mares for better breeding efficiency, to organize or to regulate heat cycles during the mare's seasonal transition, and to help maintain pregnancy. It also is used to modify estrus-related behaviors that interfere with performance and pleasure riding in non-breeding mares.
We can let your veterinarian know that you are interested in our compounded Progesterone.
When injectable progesterone is used in the non-pregnant mare to regulate the estrus cycle or synchronize estrus, it will suppress outward signs of estrus, although it will not prevent ovulation consistently. Consequently prostaglandin commonly is given at the end of a course of progesterone to cause lysis of the CL and predictable return to estrus. Injectable progesterone commonly is used for pregnancy maintenance and is accepted as safe in the pregnant and lactating mare. Pony breeds are similar to horses in their response to progesterone.
Progesterone in Oil Side Effects
The most-common side effect of progesterone in oil is injection site reaction. These reactions usually respond to hot compresses and NSAIDs.
Rifampin may decrease progesterone's activity.
No specific information was found in the literature regarding overdose in the mare. Occasionally pregnant mares that have undergone surgery or other major stress are given very high doses in an attempt to protect their pregnancy. Doses of one to two grams of injectable progesterone in oil have been given in clinical situations with no apparent detrimental effect.
May Be Prescribed by Vets for:
Control of reproductive cycle, pregnancy maintenance and behavior modification.
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Barbara Forney, VMD
Dr. Barbara Forney is a veterinary practitioner in Chester County, Pennsylvania. She has a master's degree in animal science from the University of Delaware and graduated from the University of Pennsylvania School of Veterinary Medicine in 1982.
She began to develop her interest in client education and medical writing in 1997. Recent publications include portions of The Pill Book Guide to Medication for Your Dog and Cat, and most recently Understanding Equine Medications published by the Bloodhorse.
Dr. Forney is an FEI veterinarian and an active member of the AAEP, AVMA, and AMWA.
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This content is intended for counseling purposes only. This content is informational/educational and is not intended to treat or diagnose any disease or patient. No claims are made as to the safety or efficacy of mentioned preparations. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. You are encouraged to speak with your prescriber as to the appropriate use of any medication. Wedgewood Pharmacy’s compounded veterinary preparations are not intended for use in food and food-producing animals. All product and company names are trademarks™ or registered® trademarks of their respective holders. Use of them does not imply any affiliation with or endorsement by them.