Ordering compounded medications is easier than ever. Log in with your secure digital account and gain instant access to the industry’s largest formulary of compounded medications – 24 hours a day, 7 days a week.
Ordering your pet's prescription drugs from Wedgewood Pharmacy is safe, and convenient. With a prescription number, easily refill prescriptions and enroll in the AutoRefill Program.
May Be Prescribed by Vets for:
Search for Available Dosage Forms
Itraconazole is a triazole antifungal drug that is used to treat systemic fungal-infections of dogs, cats, and humans. It also is used topically to treat ulcerative keratomycosis of horses. Triazoles are a subgroup of the azole group of drugs. These drugs are fungistatic at the concentrations used systemically and fungicidal at the concentrations that may be achieved topically.
Itraconazole is effective against a filamentous fungi, dimorphic fungi and yeasts. The mechanism of action is through the disruption of the oxidative enzymes of the fungal organism.
Topical itraconazole has been shown to be effective to treat ulcerative keratomycosis. It is particularly effective against aspergillus, one of the more-common fungal pathogens. The ophthalmic preparation of itraconazole contains 1% itraconazole, 30% DMSO, and artificial tears. This formulation is necessary because itraconazole is relatively insoluble in water.
Therapy for ulcerative keratomycosis needs to be quite aggressive. Many clinicians recommend topical treatment every two hours. Some animals with particularly difficult cases of ulcerative keratomycosis also may be treated systemically with oral itraconazole or oral lufenuron.
Uveitis may increase after the first day of therapy because of inflammation due to fungal death.
DMSO may be topically irritating in some horses.
Corticosteroids generally are contraindicated in cases of ulcerative keratomycosis. No drug interactions per se were found.
No information regarding overdose was found in the literature. Itraconazole is one of the less toxic azole drugs.
Dr. Barbara Forney is a veterinary practitioner in Chester County, Pennsylvania. She has a master's degree in animal science from the University of Delaware and graduated from the University of Pennsylvania School of Veterinary Medicine in 1982.
She began to develop her interest in client education and medical writing in 1997. Recent publications include portions of The Pill Book Guide to Medication for Your Dog and Cat, and most recently Understanding Equine Medications published by the Bloodhorse.
Dr. Forney is an FEI veterinarian and an active member of the AAEP, AVMA, and AMWA.
Some states restrict the information we may provide about controlled substances. Please select your state below.
405 HERON DRIVE SUITE 200 • SWEDESBORO, NJ 08085-1749 | © 2004-2021 WEDGEWOOD PHARMACY, ALL RIGHTS RESERVED.
This content is intended for counseling purposes only. This content is informational/educational and is not intended to treat or diagnose any disease or patient. No claims are made as to the safety or efficacy of mentioned preparations. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. You are encouraged to speak with your prescriber as to the appropriate use of any medication. Wedgewood Pharmacy’s compounded veterinary preparations are not intended for use in food and food-producing animals. All product and company names are trademarks™ or registered® trademarks of their respective holders. Use of them does not imply any affiliation with or endorsement by them.