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Dogs, cats and horses
May Be Prescribed by Veterinarians for:
Dogs and cats: Congestive heart failure (CHF), pulmonary edema, uremia, hyperkalemia, hypertension.
Horses: Exercise induced pulmonary hemorrhage, acute renal failure, edema due to a variety of causes.
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Furosemide may be administered orally, intramuscularly, subcutaneously, or intravenously. Onset of action after oral administration is approximately one hour. Onset of action after intravenous administration is five minutes with peak effect at approximately 30 minutes. Constant rate infusion may be helpful in the initial phase of treatment of animals with life-threatening CHF.
Furosemide is used in dogs and cats to promote diuresis and manage fluid retention. It is commonly used to treat pulmonary edema due to CHF. Other uses include diuresis in acute renal failure, management of ascites, hypercalcemia, or hyperkalemia. Although furosemide also lowers blood pressure through vasodilation, it is not considered a primary treatment for hypertension.
Cats are more sensitive to furosemide than dogs or other species and may need lower doses. Cats are also more likely to develop hypokalemia, azotemia and ototoxicity.
Furosemide is used in general equine practice to manage fluid retention and edema. It is commonly used in racehorses to reduce the incidence of exercise-induced pulmonary hemorrhage (EIPH) and epistaxis. The mechanism of action is through the dose-dependent reduction in right atrial, pulmonary arterial, and pulmonary capillary pressures. Furosemide has been shown to cause bronchodilation, which may also play a role in the prevention of epistaxis.
There are a number of possible drug interactions with furosemide:
Dr. Barbara Forney is a veterinary practitioner in Chester County, Pennsylvania. She has a master's degree in animal science from the University of Delaware and graduated from the University of Pennsylvania School of Veterinary Medicine in 1982.
She began to develop her interest in client education and medical writing in 1997. Recent publications include portions of The Pill Book Guide to Medication for Your Dog and Cat, and most recently Understanding Equine Medications published by the Bloodhorse.
Dr. Forney is an FEI veterinarian and an active member of the AAEP, AVMA, and AMWA.
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This content is intended for counseling purposes only. This content is informational/educational and is not intended to treat or diagnose any disease or patient. No claims are made as to the safety or efficacy of mentioned preparations. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. You are encouraged to speak with your prescriber as to the appropriate use of any medication. Wedgewood Pharmacy’s compounded veterinary preparations are not intended for use in food and food-producing animals. All product and company names are trademarks™ or registered® trademarks of their respective holders. Use of them does not imply any affiliation with or endorsement by them.