Ordering patient medications is easy. With an online account, access our extensive formulary or over 20,000 unique items - 24 hours a day, 7 days a week.
Ordering your pet's prescription drugs from Wedgewood Pharmacy is safe, and convenient. With a prescription number, easily refill prescriptions and enroll in the AutoRefill Program.
Dogs, cats and horses
Search for Available Dosage Forms
Enrofloxacin is a broad-spectrum bactericidal antibiotic. Although the mechanism of action is not well understood, Enrofloxacin is effective against a broad spectrum of gram-positive and gram-negative bacteria including most species of the following: Pseudomonas aeruginosa, Klebsiella, E.coli., Enterobacter, Campylobacter, Shigella, Salmonella, Aeromonas, Haemophilus, Proteus, Yersinia, Serratia, Vibrio, Brucella, Chlamydia, Staphylococci (including some methicillin resistant strains), Mycoplasma, and Mycobacterium.
It is not effective against anaerobic bacteria and may be variably effective against Streptococcus infections. Enrofloxacin has a similar spectrum of activity as ciprofloxacin but enrofloxacin has been shown to have better bioavailability. With the exception of cerebral spinal fluid, enrofloxacin attains therapeutic levels in most tissues of the body. This makes it a very attractive antibiotic choice for difficult-to-treat infections, particularly those that need long-term antibiotics. Some examples might be osteomyelitis, sinus infections, otitis, difficult soft tissue infections, peritonitis, and pleuritis or pneumonia.
Enrofloxacin is eliminated by both renal and hepatic metabolism. Animals with impaired kidney or liver function may need extra monitoring and dose adjustments to prevent excess drug accumulation.
Enrofloxacin is approved for use in dogs and cats. In dogs it may be given orally, intramuscularly or intravenously. It is approved only for oral use in cats although there is published information regarding intramuscular use. One of the positive features of enrofloxacin is that it is absorbed well orally and in many cases may be given once per day.
Fluorquinolones including enrofloxacin have been shown to cause articular cartilage abnormalities when the drug is given at high dose-levels. The age and breed of the patient should be considered when using enrofloxacin. Large and giant breeds may be more at risk because of a longer period of growth. Enrofloxacin has been shown to be safe in pregnant dogs and lactating dogs, however because of the problems with articular cartilage it should be avoided unless the benefits clearly outweigh the risk to the puppies. This work has not been repeated in cats.
Enrofloxacin is well-absorbed orally and intravenously. It generally is not used intramuscularly because it is too irritating. Although studies have not been done in the horse, there is the risk of developmental cartilage abnormalities with the
Fluorquinolones antibiotics. Since horses are expected to be athletes, the use of enrofloxacin in the young horse should be weighed carefully against the potential risk of cartilage abnormality.
Dr. Barbara Forney is a veterinary practitioner in Chester County, Pennsylvania. She has a master's degree in animal science from the University of Delaware and graduated from the University of Pennsylvania School of Veterinary Medicine in 1982.
She began to develop her interest in client education and medical writing in 1997. Recent publications include portions of The Pill Book Guide to Medication for Your Dog and Cat, and most recently Understanding Equine Medications published by the Bloodhorse.
Dr. Forney is an FEI veterinarian and an active member of the AAEP, AVMA, and AMWA.
Some states restrict the information we may provide about controlled substances. Please select your state below.
405 HERON DRIVE SUITE 200 • SWEDESBORO, NJ 08085-1749 | © 2004-2017 WEDGEWOOD PHARMACY, ALL RIGHTS RESERVED.
This content is intended for counseling purposes only. This content is informational/educational and is not intended to treat or diagnose any disease or patient. No claims are made as to the safety or efficacy of mentioned preparations. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. You are encouraged to speak with your prescriber as to the appropriate use of any medication. Wedgewood Pharmacy’s compounded veterinary preparations are not intended for use in food and food-producing animals. All product and company names are trademarks™ or registered® trademarks of their respective holders. Use of them does not imply any affiliation with or endorsement by them.