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Opiate Partial Agonist
May Be Prescribed by Vets for:
For mild to moderate pain
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Buprenorphine belongs to the opiate class of drugs and partially binds to opiate mu-receptors. This prevents the sensation of pain produced by brain chemicals. A synthetic opiate, buprenorphine can be used by veterinarians for the management of mild to moderate pain.
Buprenorphine is like morphine but may not include the associated gastrointestinal side-effects. Although buprenorphine has up to a 30 times stronger bond to the mu-receptors as compared to morphine, the original opiate narcotic that all others tend to be compared to in terms of potency and clinical response, it tends to exhibit less relief from severe pain sensation.
In veterinary medicine, buprenorphine is commonly prescribed for buccal administration in feline patients to treat mild to moderate pain sensation. For example, a veterinarian can prescribe buprenorphine to manage pain associated with tissue inflammation due to infection or pathological disease, tissue spasms, and trauma.
As with many other drug therapies in veterinary medicine, buprenorphine is approved by the FDA only for use in humans, not animals. However, veterinarians have been able to prescribe the drug as an extra label medication under the Animal Medicinal Drug Use Clarification Act.
The Drug Enforcement Agency (DEA) regulates buprenorphine. Buprenorphine tends to be administered onsite at the prescribing veterinary clinic or hospital.
Allergic or hypersensitive patients should not be given buprenorphine. Buprenorphine is not recommended for use in animals with Addison's disease and kidney disease. Geriatric patients and animals with liver disease, severe head trauma, or cardiovascular conditions can require close monitoring throughout treatment.
As with all forms of drug therapy, buprenorphine treatment has potential side-effects. The most-common side effect is sedation.
Dr. Evan Ware is a veterinary practitioner in Phoenix, Arizona. He received both his undergraduate degree in microbiology and his Doctorate of Veterinary Medicine from The Ohio State University.
Dr. Ware is currently the Medical Director of University Animal Hospital (VCA) and is also the owner of two other hospitals, including Laveen Veterinary Center and Phoenix Veterinary Center. His areas of interest include orthopedic medicine and surgery, veterinary oncology and chemotherapy, and general and advanced soft-tissue surgery.
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This content is intended for counseling purposes only. This content is informational/educational and is not intended to treat or diagnose any disease or patient. No claims are made as to the safety or efficacy of mentioned preparations. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. You are encouraged to speak with your prescriber as to the appropriate use of any medication. Wedgewood Pharmacy’s compounded veterinary preparations are not intended for use in food and food-producing animals. All product and company names are trademarks™ or registered® trademarks of their respective holders. Use of them does not imply any affiliation with or endorsement by them.