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Beta Adrenergic Blocker
Dogs and cats
May Be Prescribed by Veterinarians for:
Cardiac arrhythmias and hypertension
Atenolol is commercially available as Tenormin® (25mg/50mg/100mg tablets)
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Atenolol is a beta adrenergic blocker that is used in veterinary medicine to treat supraventricular tachyarrhythmia, premature ventricular contractions (PVC’s), and systemic hypertension. Beta blockers improve cardiac performance indirectly by reducing the heart rate; prolonging diastole, which allows more time for ventricular and coronary arterial filling.
The effects of atenolol on the cardiovascular system include decreased sinus heart-rate, slowed AV conduction, decreased cardiac output and oxygen demand, and decreased blood pressure. Beta-blockers may be cardioprotective in early cases of hypertrophic cardiomyopathy because they reduce myocardial oxygen demand. Atenolol is most commonly used with other cardiac anti-arrhythmic drugs.
The bioavailability of atenolol is higher in dogs (80%) and cats (90%) than in humans. Atenolol undergoes minimal hepatic metabolism and is eliminated in the urine and to a lesser extent in the feces.
Dogs: Atenolol is used in dogs to treat arrhythmias, hypertension, obstructive heart disease, subvalvular aortic stenosis, and pulmonic stenosis. Atenolol may be used with other drugs, such as calcium channel blockers and ACEI drugs, in the treatment of systemic hypertension. When atenolol is used to treat atrial fibrillation in dogs, it is frequently used with digoxin.
Cats: Atenolol is used in cats to treat hypertrophic cardiomyopathy (HCM), left ventricular outflow tract obstruction, and hypertension secondary to hyperthyroidism.
She began to develop her interest in client education and medical writing in 1997. Recent publications include portions of The Pill Book Guide to Medication for Your Dog and Cat, and most recently Understanding Equine Medications published by the Bloodhorse.
Dr. Forney is an FEI veterinarian and an active member of the AAEP, AVMA, and AMWA.
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