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Prazosin is a drug that is used in dogs and cats to treat high blood pressure, congestive heart failure, and spasm of the urethra. Prazosin causes the small blood vessels to relax (vasodilation). This makes it easier for blood to circulate, decreasing blood pressure and the work load on the heart. High blood pressure can be controlled or managed by drugs such as prazosin, but these drugs do not cure the underlying medical problem. Like many other drugs in veterinary medicine, this drug is not FDA approved for use in animals and is not available from a veterinary pharmaceutical manufacturer. Instead, it is compounded by a specialty pharmacy.
Give this medication to your pet exactly as your veterinarian prescribes. If you miss giving your pet a dose of prazosin, give the next dose as soon as you remember or, if it is close to the next scheduled dose, return to the regular schedule. Do not double dose to catch up.
Prazosin should be given with food.
Wash your hands after giving your pet this medication.
Be sure to discuss any side effects with your veterinarian immediately.
Most side effects occur at the beginning of treatment. They can include dizziness or even fainting when your animal first stands up. Other side effects are related to the digestive tract and can include vomiting, diarrhea, or constipation.
Keep this and all drugs out of reach of children. This drug should only be given to the animal for which it was prescribed. Do not give this medication to a person.
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Prazosin should not be used in animals with low blood pressure or those with chronic kidney problems.
Be sure to review with your veterinarian any medications or supplements your pet may be receiving.
Other drugs that lower blood pressure are generally not used with prazosin. This includes beta blockers, sildenafil, verapamil, and nifedipine.
Clonidine may decrease the effects of prazosin.
If you suspect your pet or another animal has been accidentally overdosed or has eaten this medication inadvertently, contact your veterinarian or the A.S.P.C.A.'s Animal Poison Control Center at 888.426.4435. Always have the prescription container with you when you take your pet for treatment.
If you or someone else has accidentally ingested this medication call the National Capital Poison Center at 800.222.1222.
Different strengths or dosage forms of prazosin may have different storage requirements. Read the label or ask your pharmacist for the storage requirements of the prescription you receive.
Dr. Barbara Forney is a veterinary practitioner in Chester County, Pennsylvania. She has a master's degree in animal science from the University of Delaware and graduated from the University of Pennsylvania School of Veterinary Medicine in 1982.
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This content is intended for counseling purposes only. This content is informational/educational and is not intended to treat or diagnose any disease or patient. No claims are made as to the safety or efficacy of mentioned preparations. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. You are encouraged to speak with your prescriber as to the appropriate use of any medication. Wedgewood Pharmacy’s compounded veterinary preparations are not intended for use in food and food-producing animals. All product and company names are trademarks™ or registered® trademarks of their respective holders. Use of them does not imply any affiliation with or endorsement by them.