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Demecarium Bromide Ophthalmic for Dogs


General Drug Information and Indications
How to Give this Medication
Side Effects
Drug Interactions
Search for Available Dosage Forms

General Drug Information and Indications

Demecarium bromide is a potent, long-acting ophthalmic drug used to treat acute glaucoma in dogs. It has been shown to decrease pressure within the eye for up to 48 hours. Like many other drugs in veterinary medicine, this drug is not FDA approved for use in animals and is not available from a veterinary pharmaceutical manufacturer. Instead, it is compounded by a specialty pharmacy.

How to Give this Medication

Give this medication to your pet exactly as your veterinarian prescribes. If you miss giving your pet a dose of demecarium bromide, give the next dose as soon as you remember or, if it is close to the next scheduled dose, return to the regular schedule. Do not double dose to catch up.

One of the advantages of demecarium bromide is that it may be administered only once or twice a day.

Demecarium bromide is frequently also prescribed for the non-affected eye. In almost all cases of glaucoma in one eye, the non-affected eye will also develop glaucoma if it is not monitored and appropriately medicated.

Administering eye medications to animals can be a struggle and may require patience and practice. Try not to touch the tube or container tip to your dog’s eye or eyelid. It is also important to not contaminate the medication by touching the tip with your fingers or hand. Your veterinarian can help you develop a technique that will be effective and minimally stressful for both you and your dog.

Wash your hands after giving your pet this medication.

Side Effects

Be sure to discuss any side effects with your veterinarian immediately.

Local inflammation of the eye (Iritis) may occur with demecarium bromide. Topical ophthalmic corticosteroid drops or ointment may be prescribed to diminish irritation.

Systemic side effects are generally related to digestive distress (vomiting and diarrhea) although heart related symptoms are possible. Particular care should be exercised with small breed dogs, or when high doses are used.


Keep this and all drugs out of reach of children. Demecarium bromide is a prescription drug and should be used according to your veterinarian’s directions. It should only be given to the animal for which it was prescribed. Do not give this medication to a person.

Demecarium bromide should not be used during pregnancy.

There are two classifications of glaucoma, primary and secondary and they have different causes. Demecarium bromide is only used in animals with primary glaucoma.

Drug Interactions

Be sure to review with your veterinarian any medications or supplements your pet may be receiving.

Demecarium bromide should be used with caution with other drugs from the same family: carbamate or organophosphate drugs or succinylcholine because of the increased chance of systemic side effects.

If you’re vet has prescribed additional ophthalmic medications for your pet, give the medications 5-10 minutes apart.


Overdose may cause GI distress, low blood pressure, low heart rate and difficulty breathing.

If you suspect your pet or another animal was overdosed accidentally or has eaten this medication inadvertently, contact your veterinarian or the A.S.P.C.A.’s Animal Poison Control Center at 888.426.4435. Always bring the prescription container with you when you take your pet for treatment.

If you or someone else has accidentally ingested this medication call the National Capital Poison Center at 800.222.1222.


Different strengths or dosage forms of demecarium bromide may have different storage requirements. Read the labeling or ask your pharmacist for the storage requirements of the prescription you receive.

The information contained on this site is general in nature and is intended for use as an informational aid. It does not cover all possible uses, actions, precautions, side effects, or interactions of the products shown, nor is the information intended as medical advice or diagnosis for individual health problems or for making an evaluation as to the risks and benefits of using a particular product. You should consult your doctor about diagnosis and treatment of any health problems. Information and statements have not been evaluated by the Food and Drug Administration ("FDA"), nor has the FDA approved the products to diagnose, cure or prevent disease. 

Wedgewood Pharmacy compounded veterinary preparations are not intended for use in food and food-producing animals.
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About the Author

Dr. Barbara Forney is a veterinary practitioner in Chester County, Pennsylvania. She has a master's degree in animal science from the University of Delaware and graduated from the University of Pennsylvania School of Veterinary Medicine in 1982.

She began to develop her interest in client education and medical writing in 1997. Recent publications include portions of The Pill Book Guide to Medication for Your Dog and Cat, and most recently Understanding Equine Medications published by the Bloodhorse.

Dr. Forney is an FEI veterinarian and an active member of the AAEP, AVMA, and AMWA.