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Idoxuridine is a topical antiviral drug used in the treatment
of ocular herpetic lesions in cats. It is virustatic rather than virucidal. The
substitution of idoxuridine for thymidine in the viral DNA causes a misreading
of the genetic sequence and consequently the virus is unable to replicate.
Idoxuridine is a topical anti-viral ophthalmic preparation used in the treatment of Feline Herpes Virus, FHV. Severe naso-ocular signs, with corneal ulceration are commonly seen with FHV. In addition FHV can have a variety of more chronic ocular presentations including chronic conjunctivitis, tear duct blockage or infection, corneal ulcerative keratitis, stromal keratitis, eosinophillic keratitis, and anterior uveitis. Idoxuridine is generally well tolerated. It penetrates the conjunctiva and cornea poorly except where there is ulceration, requiring frequent application. Treatment will take weeks and should continue for an additional week past the resolution of all clinical signs.
• Some local irritation.
• Idoxuridine should not be used with topical ophthalmic
corticosteroids in the treatment of corneal ulceration.
• None found.
• Recommended dose interval is every 2-3 hours, overdose is unlikely to occur.
Dr.
Barbara Forney is a veterinary practitioner in Chester County, Pennsylvania.
She has a master's degree in animal science from the University of Delaware
and graduated from the University of Pennsylvania School of Veterinary Medicine
in 1982.
She began to develop her interest in client education and medical writing 1997. Recent publications include portions of The Pill Book Guide to Medication for Your Dog and Cat, and most recently Understanding Equine Medications published by the Bloodhorse.
Dr. Forney is an FEI veterinarian and an active member of the AAEP, AVMA, and AMWA.
You can purchase books by Dr. Forney at www.exclusivelyequine.com
The information contained on this site
is general in nature and is intended for use as an informational aid. It does
not cover all possible uses, actions, precautions, side effects, or interactions
of the products shown, nor is the information intended as medical advice or
diagnosis for individual health problems or for making an evaluation as to the
risks and benefits of using a particular product. You should consult your doctor
about diagnosis and treatment of any health problems. Information and statements
have not been evaluated by the Food and Drug Administration ("FDA"),
nor has the FDA approved the products to diagnose, cure or prevent disease.
Wedgewood compounded veterinary preparations are not intended for use in food and food-producing animals.
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