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Idoxuridine for Veterinary Use
By Barbara Forney VMD

 
Overview
Therapeutic Class
Topical anti-viral ophthalmic drug
Species
Cats
Commonly prescribed by vets for:
Feline ocular herpes virus infection
   

Basic Information

Idoxuridine is a topical antiviral drug used in the treatment of ocular herpetic lesions in cats. It is virustatic rather than virucidal. The substitution of idoxuridine for thymidine in the viral DNA causes a misreading of the genetic sequence and consequently the virus is unable to replicate.

Cats

Idoxuridine is a topical anti-viral ophthalmic preparation used in the treatment of Feline Herpes Virus, FHV. Severe naso-ocular signs, with corneal ulceration are commonly seen with FHV. In addition FHV can have a variety of more chronic ocular presentations including chronic conjunctivitis, tear duct blockage or infection, corneal ulcerative keratitis, stromal keratitis, eosinophillic keratitis, and anterior uveitis. Idoxuridine is generally well tolerated. It penetrates the conjunctiva and cornea poorly except where there is ulceration, requiring frequent application. Treatment will take weeks and should continue for an additional week past the resolution of all clinical signs.

Side Effects

• Some local irritation.

Precautions

• Idoxuridine should not be used with topical ophthalmic corticosteroids in the treatment of corneal ulceration.

Drug Interactions

• None found.

Overdose

• Recommended dose interval is every 2-3 hours, overdose is unlikely to occur.

About the Author

Dr. Barbara Forney is a veterinary practitioner in Chester County, Pennsylvania. She has a master's degree in animal science from the University of Delaware and graduated from the University of Pennsylvania School of Veterinary Medicine in 1982.

She began to develop her interest in client education and medical writing 1997. Recent publications include portions of The Pill Book Guide to Medication for Your Dog and Cat, and most recently Understanding Equine Medications published by the Bloodhorse.

Dr. Forney is an FEI veterinarian and an active member of the AAEP, AVMA, and AMWA.

You can purchase books by Dr. Forney at www.exclusivelyequine.com

The information contained on this site is general in nature and is intended for use as an informational aid. It does not cover all possible uses, actions, precautions, side effects, or interactions of the products shown, nor is the information intended as medical advice or diagnosis for individual health problems or for making an evaluation as to the risks and benefits of using a particular product. You should consult your doctor about diagnosis and treatment of any health problems. Information and statements have not been evaluated by the Food and Drug Administration ("FDA"), nor has the FDA approved the products to diagnose, cure or prevent disease.

Wedgewood compounded veterinary preparations are not intended for use in food and food-producing animals.

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